The Neutral Model of evolution and recent African origins

by Robert Carter

The Recent African Origins (RAO) theory is on tenuous ground. It relies deeply on the Standard Neutral Model of evolution (SNM), but every assumption behind SNM and, therefore, RAO has been openly questioned in the evolutionary literature. If real-world populations violate the central assumptions of SNM, the conclusions of studies that assume SNM are not the final word on the subject. The real situation is much more complicated than the simplifying assumptions allow, and several of these assumptions are either biased in favour of the conclusion or are contrary to the data: crossing over is not random, population structure exists at all scales, and population admixture and gene conversion overly complicate the models. The presence of natural selection among human mitochondria removes the ‘neutral’ part of SNM as far as RAO’s ‘Mitochondrial Eve’ is concerned. Finally, RAO and SNM are based on the belief that evolution can occur, but that it cannot affect the things that control the speed of evolution. There is no room for differences in mutation rates among populations caused by environmental stress, nutrition, demographics or mutations in the DNA copying, proofreading or correcting mechanisms. The most popular evolutionary model of recent human evolution is unsatisfactory, but the biblical model for human genetic history is still in its infancy. Outlined are several lines of thought that may be productive to creationist research.

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‘The challenge of genetic studies of human history is to use the small amount of genetic differentiation among populations to infer the history of human migrations’ (Rosenberg et al. 2002¹).

Figure 1. This map shows the Recent African Origins concept in detail. According to RAO theory, modern humans originated in Africa, diversified there, and then one lineage (with several major clades) migrated away to populate the rest of the world. This is very similar to the biblical concept, only with a different starting point (Middle East) and a different time frame. (From MITOMAP: A Human Mitochondrial Genome Database, , 2008).

This quote illustrates an important point. Modern geneticists are struggling to understand human genetic history. In the end, they are forced to make certain inferences based on limited data and a suite of simplifying assumptions. The purpose of this article is to look at the underpinnings of the Recent African Origins (RAO) model of human evolution, first popularized by claims of the discovery of ‘Mitochondrial Eve’ in Africa.² Each of the fundamental assumptions behind the theory has been openly questioned in the evolutionary literature. If any one of the assumptions behind RAO falls, the entire theory may be made moot. By listing the assumptions and then systematically showing how each one is impractical, impossible, contradictory or biased in favour of evolutionary theory, I hope to bring RAO down a few notches.

The term ‘recent’ is used by RAO supporters in a deep-time sense and is not meant, by them, to be taken as support of a young Earth. According to RAO, humans evolved in Africa, existed as a small population for some hundreds of thousands of years, and then rapidly expanded into the rest of the world about 200,000 years ago. As an explanatory tool, it stands in direct opposition to the biblical model, where the most important genetic signals should be the Creation (which limits overall human diversity), the Flood (a bottleneck event), and the Tower of Babel event (which led to significant population subdivision and a world-wide migration). The last two are expected to yield similar results to the hypothetical RAO model, but with a different timescale.
I will caution the reader at this point. This article might seem to overthrow all arguments based on neutral evolution or bottleneck theories (both terms will be defined below). Creationists sometimes use those theories to their advantage, and it is not my intent to completely discount them. In fact, RAO uses much of the same mathematics many creationists would like to apply to the biblical model. My intent is to take a more ‘surgical’ approach, cutting out the ‘cancer’ of bad science, while leaving untouched any science that may yet be valid and useful. And in arguing against RAO, I am actually arguing for a more recent origin of humanity, though this is not my focus here and will not come through strongly in this article.

The goal of this paper is to highlight the places where they make unrealistic assumptions in their favour, and, by pointing out how unrealistic these assumptions are, I hope to dispel some of the RAO [Recent African Origins] mythology.

RAO makes a number of approximations, as do all theories by necessity. For this reason, almost any theory can be attacked for being ‘unrealistic’. The goal of this paper is to highlight the places where they make unrealistic assumptions in their favour, and, by pointing out how unrealistic these assumptions are, I hope to dispel some of the RAO mythology.

RAO does not support large-scale, deep-time evolution. There is nothing evolutionary about humans moving out of, or into, Africa at any time. Rather, the importance of the theory lies in the issue of dating and rooting the human genealogical tree. The following quote from the seminal RAO paper is going to be the focus of everything that follows: ‘We infer … that Africa is a likely source of the human mitochondrial gene pool. This inference comes from the observation that one of the two primary branches leads exclusively to African mtDNAs …, while the second primary branch also leads to African mtDNAs.’² If we can dissect this, we will be far along the road to a better theory of human genetic history (figure 1).

The Standard Neutral Model of evolution

RAO is based on the Standard Neutral Model of evolution (SNM), itself being based on a long line of theoretical arguments, starting with J.B.S. Haldane’s writings in the 1950s. It is important to understand the development of this theory if we are to understand RAO.
Haldane (1957)³ was the first to discuss the concept known as the ‘cost of substitution’. According to Haldane, natural populations should not be able handle the number of deaths required by natural selection to drive positive evolution. Put simply, higher vertebrates do not have a high enough reproductive rate to support rapid rates of beneficial evolution. It takes too many deaths (the ‘cost’) to select for new mutations. Many creationists argue ‘Haldane’s Dilemma’ has not been sufficiently answered to date.⁴

Figure 2. The tree that started it all. Cann et al.² based their ‘Out of Africa’ conclusion on the fact that the first major branch in their tree leads to all African sequences on one side and mixed African/world sequences on the other. This conclusion is based on a suite of assumptions that are discussed at length in the text. (From figure 3 of Cann et al.²).

Motoo Kimura took Haldane’s argument one step further by applying it to measured genetic differences between mammals. Following Haldane, he reasoned that if the genetic differences between two species were all due to positive selection, and if they evolved within the standard evolutionary timescale, then mammals would have needed an astronomically high reproductive rate to give natural selection enough fodder to drive evolutionary changes. For example, humans and chimpanzees have millions of genetic differences, but 3 million years would give us only about 100,000 human generations in which to fix these millions of differences. According to evolutionary calculations, natural selection would have had to remove many times more people than could possibly have been born during this time in order fix this many differences. To solve the dilemma, Kimura reasoned the majority of new mutations must be ‘neutral’ (this is the origin of the belief that most of the genome is composed of ‘junk DNA’, a term discussed elsewhere in this journal⁵). The rate of neutral evolution could be much faster than positive evolution, and would be limited only by the rate of DNA copying errors. Since natural selection will not act on neutral traits, which do not affect survival or reproduction, neutral evolution can proceed through random drift without any inherent cost of selection. Kimura saw Haldane’s Dilemma as a serious problem and listed it as his main reason for proposing the Neutral Theory of evolution.⁶ Haldane was right, Kimura asserted, but the preponderance of biological change must be neutral.
The Neutral Model has been expanded by many authors to become what we will call the Standard Neural Model (SNM). SNM was developed to cover complex historical patterns such as bottleneck events. It is the fundamental underpinning of RAO.
The following is a list of assumptions critical to the RAO model. Note how SNM is intrinsic to RAO theory (figure 2):
Constant population size. Although the Neutral Model is unaffected by population size, SNM was developed partly to model changes in population size (specifically one cycle of population bottleneck). RAO assumes a single human population with a single expansion event and no subsequent sub-population bottlenecks or other demographic differences.
Random mating (no population substructure, geographic or otherwise). Again, Neutral Theory is not contingent upon random mating, but RAO is. Population substructure prior to or after the Out of Africa Event might hide the true picture of human demographic history.
Neutral polymorphisms. There can be no selection acting on the alleles under question. RAO is based on the assumption that the entire mitochondrial genome is essentially neutral, or at least that negative mutations are efficiently eliminated. For detailed critique of this, see Sanford.⁷
An infinite-sites model of mutation. There cannot be multiple mutations at identical sites in different lineages and back mutations are not allowed. In some sense, this is a reasonable approximation, given the large size of the genome and the small number of generations involved (in the Creation model) or with the low rate of mutation (in evolutionary models). The approximation also simplifies the theoretical understanding and calculations. However, if this approximation turns out to be incorrect, RAO becomes harder to understand and the calculations behind it become less tenable.
Constant mutation/substitution rate among all subpopulations (the ‘molecular clock’). To illustrate how critical this is, I will quote Cann et al.:² ‘A time scale can be affixed to the tree … by assuming that mtDNA sequence divergence accumulates at a constant rate’.

Figure 3. Simplified mtDNA tree from . This diagram shows the relationship among the major mitochondrial lineages. Because it is not presented in a traditional tree format, it is easy to see how difficult it is to determine where the ancestral sequence should be placed. Carter³⁹ placed the root not in Africa, but at the ’R’located close to the centre of the tree. (From MITOMAP: A Human Mitochondrial Genome Database, , 2008).

Constant effective generation time among all subpopulations (typically assumed to be 20 years for humans, although values between 20 and 30 have been used by various authors).
A human-chimp common ancestor some 3–6 million years ago. This is not an assumption of SNM, but is needed for calibrating the SNM bottleneck event. Essentially, by counting the number of differences between chimp and human mitochondria, and by then dividing this number by 3 to 6 million, one can get an estimate of the number of mutations that supposedly accumulate in the populations per year.

Tajima’s D statistic

Tajima’s D statistic⁸ is used to test SNM along a given stretch of DNA. It is basically a summary of the allele frequency spectrum. D values not significantly different from zero indicate the population meets all the criteria for SNM. Positive and negative values are due to an overabundance or dearth in the expected number of rare polymorphisms, respectively. Significant positive or negative values of D may indicate the presence of natural selection or historic changes in population size or multi-population introgression. This is an important metric for both SNM and RAO theory.

Historic changes in population size are expected to influence Tajima’s D statistic in that population growth should lead to excess low-frequency polymorphisms (negative D-values). This occurs because new mutations are carried along with the expansion and do not exit the population as easily through random drift. Alternatively, population bottlenecks should lead to a deficiency in low-frequency polymorphisms (positive D-values) because most low frequency alleles are eliminated through random selection.

Linkage disequilibrium

SNM needs to be put in the context of sexual reproduction. During gamete production, crossing over occurs between chromosome copies. This mixing causes randomization of the alleles (variations) along a stretch of DNA. However, because there are only one or two crossing over events per chromosome arm per generation, not all alleles are randomized each generation. And, the closer two alleles are, the less likely they are to be separated. Alleles in close proximity are said to be ‘linked’. This is also true of alleles separated by regions of infrequent crossing over. Geneticists use the term ‘linkage disequilibrium’ (LD) to describe the unequal association of certain alleles with certain other alleles. A set of alleles inherited together are referred to as a ‘haplotype’.
Population growth not only leads to negative D values (excess low frequency alleles), it also leads to less LD because crossing over randomizes more and more alleles each generation. Alternatively, population bottlenecks should lead to higher LD because during a bottleneck event a small number of people pass their large linkage blocks on to the entire population. It takes time for the haplotypes to be scrambled.

Expectations of SNM

The population parameters used in SNM calculations must be estimated, and this is no easy task. For humans, the mutation rate is based on current levels of genetic diversity, the assumption that the vast majority of that genetic diversity is neutral, and an assumed chimp-human ancestor 3–6 Ma. In other words, the calculation assumes large-scale evolution (i.e. macroevolution) is true. The effective population size (N_e) is also estimated from observed levels of diversity. But N_e is also dependent upon the generation time and the time to a common ancestor, two parameters about which little is known.⁹ Given an equal number of males and females and random mating, the ratio of hypothetical N_e for the autosomes, X chromosome, non-recombining portion of the Y chromosome (NRY), and mtDNA is 4:3:1:1, respectively. The reduced N_e is expected to produce more rapid differentiation among populations for the haploid loci than for the others.¹⁰ This is one reason why RAO was initially based on mitochondrial sequences.

The bottleneck event associated with the Flood would have created a strong signal that should still be evident today. Any model of human history that does not take this into account will come to incorrect conclusions if the Flood story is accurate.

Since the calculation of the time to a most recent common ancestor (TMRCA) is directly proportional to N_e, TMRCAs for the autosomes and the X chromosome are expected to be 4 and 3 times greater, respectively, than for the two haploid loci.¹⁰ But this ignores the possibility that there was only one male lineage (Noah’s Y chromosome) and only three female lineages (the mitochondrial chromosomes of Noah’s three daughters-in-law) in the founding human population. The bottleneck event associated with the Flood would have created a strong signal that should still be evident today. Any model of human history that does not take this into account will come to incorrect conclusions if the Flood story is accurate.
SNM assumes that differences in LD among populations are due to differences in demographic history.^11,12 This assumption depends, of course, on a constant rate of recombination, mutation and gene conversion in all subpopulations and a lack of ancient population structure (all of which affect LD). However, all it takes is one change in a DNA repair enzyme, one change in a gene that affects the rate of recombination, or one change in a gene that affects the process of gene conversion in one of the populations and the SNM results will diverge from reality. Thus, SNM assumes populations do not diverge in respect to certain genetic traits but are free to diverge in respect to others. This is perhaps the most critical point to understand.
According to SNM, low frequency alleles should be generally younger. As new alleles appear in the population, most of them will be lost through random drift. In fact, a new allele has a 1/N_e chance of eventually becoming fixed. In large stable populations, nearly all low frequency alleles are expected to be young. Younger alleles are also generally associated with longer haplotypes than high frequency alleles¹³ since it takes time to break down linkage blocks and shuffle new alleles in relation to older ones. Recombination is assumed to be neutral and random and to occur at a higher rate than mutation.¹⁰
By definition, the more linkage blocks a population has, the greater its expected ability to maintain polymorphism (linkage increases the variance of the numbers of polymorphic sites¹⁴). Higher levels of N_e also allow a population to maintain polymorphism (and a higher numbers of linkage blocks). The conclusion that African populations have maintained a larger long-term effective population size than non-African populations¹⁴ is based on the levels of polymorphism found in the populations, under the assumptions of SNM. But are the assumptions valid?

Violations of SNM

Violations of every assumption behind SNM have been detected and published in the evolutionary literature. Real-world populations do not conform to the constraints of SNM. Therefore, we must be careful when reading the conclusions of the many studies that have been based on this evolutionary theory.

Therefore, violations of SNM [Standard Neutral Model] should be expected to occur frequently. One may rightly question the utility of a model that cannot be fit to real-world data.

SNM is a necessary simplification that allows for the study of a highly complex system. However, violations of SNM are expected at all levels: population structure, subpopulation bottlenecks, small-scale variations in recombination rates and multi-population admixture all increase estimates of LD⁹ and interfere with SNM calculations. Also, haplotype patterns can be disrupted by recurrent mutation, gene conversion, genome assembly errors and errors in genotyping.¹² When deviations from the SNM occur (e.g. the conclusions of the majority of studies performed on the European population), the meaning of the estimated population parameters is unclear.¹⁴ In the real world, it is understood that generations overlap, that N_e fluctuates over time, that gene flow between populations changes over time and that population structure occurs within populations worldwide. Therefore, violations of SNM should be expected to occur frequently. One may rightly question the utility of a model that cannot be fit to real-world data.

N_e

One needs a good estimate of N_e in order to perform most SNM calculations, but N_e estimates are affected by several parameters, the effects of which must often be discounted in order for the model to run. Calculations of long-term N_e are disproportionately affected by low values (population contractions):¹⁰ therefore, the reported values should tend to be underestimates. Generation time also heavily influences N_e . In general, greater generation times are expected to result in proportionally lower N_e (and visa versa). Most LD studies assume generation times are equal among populations, something that cannot be historically proven. Cultural as well as genetic differences may lead to differences in generation times. Also, estimates of generation time from modern genealogical data are greater than the 20-year generation time commonly assumed in these studies (for example, 10 generations in my family tree = 300 years, or 30 years/generation). And, according to the biblical data, there should not be a constant generation time, because generation time decreased significantly immediately after the Flood.
Higher levels of N_e are expected to result in less genetic drift, slowing the divergence of populations. Human N_e has often been estimated to be about 10,000 people. Interestingly, due to their calculated inbreeding coefficient, Reich et al.¹¹ estimated a historic human Ne of ‘50 individuals for 20 generations; 1,000 individuals for 400 generations; or any other combination with the same ratio.’ I would like to point out that 5 individuals for 2 generations fits their ratio and corresponds roughly with with biblical expectations. Is this evidence of the Flood (six people for one generation), or are these calculations so entrenched in evolutionary theory that they are not useful? Frisse et al.¹⁴ found disagreement between estimates of N_e for non-African populations based on LD and polymorphism data. This is another example of real population data in conflict with SNM assumptions. Which N_e should one use?
For unexplained reasons, the estimate of a historic human N_e of 10,000 individuals is much less than N_e estimates for the great apes.¹⁰ There is a huge amount of diversity among living chimpanzees:¹⁵ perhaps as much as three to four times as much diversity as within the entire human population.¹⁶ Does this evidence support evolution under an SNM scenario, or is the diversity not so much evidence of ancient N_e as much as it is evidence of a chimpanzee genome in rapid decline?
The calculation of N_e assumes deep time. In the biblical model, calculations of N_e are not done for there is no assumption of long ages. Rather, we say that there was a population bottleneck some 4,500 years ago (the Flood) where the world population was reduced to 3 founding couples (Noah’s sons and daughters-in-law).

Non-random crossing over events

Because we do not know much about the mechanism controlling crossing over events, nor the frequency in which they occur, it is often assumed that crossing over is more or less random. This allows for easier calculations of LD. However, the phenomenon is not entirely random. Recombination ‘hot spots’ have been known for years. It is believed that there is extensive fine-scale variation of recombination frequency within the human genome, and models that incorporate recombination hot spots are often better than ones that assume random recombination.¹⁷ We need to get a better understanding of recombination in order to better understand human genetic history. There is much room for improvement and much hope for the biblical model of human origins in this subject. The very presence of long, unmixed linkage blocks suggests a young genome, but we need more data.

Population structure

Random mating, or lack of population structure (specifically for sub-Saharan African population prior to the Out of Africa dispersion), is another key assumption behind the SNM. The effective rate of recombination is expected to be reduced in structured populations because haplotypes constrained within the various subpopulations will not have a chance to recombine as often as they would under panmixia.¹⁸ Importantly, failure to recognize population structure can lead to false positives when testing for constant N_e.¹ When discussing the possibility of population structure in the presumed ancestral African population, Garrigan and Hammer¹⁰ worried that ancestral population structure could have had the effect of increasing ancestral N_e, thus throwing off their calculations. Behar et al.¹⁹ claimed that the early evolutionary history of man in Africa involved small and isolated tribes existing independently for thousands of years. This is a critical issue, for small and isolated populations experience inbreeding, rapid drift and the rapid accumulation of new mutations. The situation violates the fundamental assumptions behind the SNM while providing potentially excellent material to support the biblical model: for if several of the sub-Saharan African populations existed in such a condition after the Flood, this might go a long way in explaining why there is more genetic diversity among people of African descent.
The random mating model ignores reality, for population structure is a fact of human existence.²⁰ Individuals have a tendency to choose mates from the same social groups²¹ and subpopulations in close proximity may be completely isolated from one another. In a study by Bulayeva et al.,²² they showed through genealogical analysis that in a certain village of 2,700 people in Daghestan, only 10 marriages had been consummated by the villagers with outside people over nine generations! And most of these marriages were with neighbouring villages. Bamshad et al.²³ showed that the Hindu caste system has preserved a significant event in history—a huge invasion of India from the northwest. Men and women from upper castes are genetically more similar to Eastern Europeans, while those from lower castes are more similar to SE Asians. The religious system among a significant proportion of the Indian population has prevented free mixing for thousands of years! All this says that a realistic model of human demographic history would be overly complex,¹⁸ especially if it uses the wrong model of human history. A highly complex model may not be needed however (e.g. Liu et al. 2006²⁴), but there are always dangers involved in oversimplification.

Population admixture

Not only is the assumption of no population structure invalid (both world-wide and within subpopulations), but the situation is made more complicated by the mixing of once-separated populations. When previously separated populations come back together, heterozygosity increases. The mixing of haplotypes that arose separately causes an increase of calculated LD, even at unlinked sites.¹⁴ Admixture causes substantial variation in genetic ancestry among individuals in a population.¹ Interestingly, the block characteristics of a mixed population should be most similar to the populations with the lowest LD.²⁵ In other words, mixing can mask significant amounts of LD. For example, the fascinating admixture of African Bantu females and Jewish males (the ancestors of the Lemba tribes in SE Africa) has created a population with an unusually large number of long linkage blocks (long-distance LD).²⁶

Gene conversion

While LD is known to decrease due to the effects of crossing over, another, less well-known process called ‘gene conversion’ may be at work as well. Essentially, gene conversion is a process by which a section of DNA can copy itself onto a highly similar section of DNA in close proximity. It has been studied extensively in yeast but relatively little is known about the process in mammals.^9,14,24 It is expected that gene conversion acts over short distances, breaking down LD between closely-linked markers where crossing over is less likely.^9,14 If gene conversion is allowed in a model, calculations of N_e based on the crossing over parameter get much smaller.¹⁴ Even though little is known about gene conversion, one recent study concluded that models using crossing over plus gene conversion fit the data better than models with crossing over alone.¹⁸ However, the possibility of recurrent mutations complicates this picture by theoretically inflating the apparent level of recombination and biasing gene conversion rates upwards.¹⁴ Furthermore, high levels of recurrent mutation can make the phylogenetic signal completely invisible.²⁷
Due to gene conversion, the term ‘NRY’ (the non-recombining portion of the human Y chromosome) is technically a misnomer, for extensive gene conversion (a form of recombination) has been detected in the male-specific regions of the Y chromosome.^28,29 It is expected that high levels of gene conversion will slow divergence rates because they systematically eliminate mutational events.

Equivalent mutation rates and active selection

One of the central assumptions behind SNM is that equivalent genetic sequences in diverse populations evolve in a clock-like manner. This can only happen if selection is not acting upon the genetic sequences under question and if mutation rates are equal among all populations. However, there is evidence that a molecular clock is not operating within related clades of African mitochondrial haplogroup L2. Two of the four clades studied by Torroni et al.³⁰ were ‘disproportionately derived’ and they concluded that their results were ‘not consistent with a simple model of neutral evolution with a uniform molecular clock.’ Howell et al.³¹ indicated that there may be clock violations for all African L mitochondrial haplogroups and that there were differences in clock rates between coding and control regions. Friedlaender et al.³² went so far as to say that the variable mutation rates among mtDNA clades bring the utility of coalescent statistics and associated age estimates into question.
These are key findings, for the deep-rooting branches of the sub-Saharan lineages are foundational to RAO theory. If no molecular clock is operating among them, there is no way to time the African diaspora. And the only basis for claiming these lineages are ancestral is that they are more divergent from the rest of the world population … but how they became so divergent would then be an open question.
Other studies have concluded that deviations from SNM in Europe and Asia may be due to natural selection. Also, natural selection may not be equal among all clades, especially since clades are not distributed equally across all environmental regions.^33,34
Cultural factors may also mimic selection. Genghis Khan is ancestor to a surprising number of people in Central and Eastern Asia and is ancestor to perhaps 0.5% (1 out of 200!) of the world’s population.³⁵ If we did not know about the existence of Genghis Khan from historical sources, how would this missing information affect our conclusions about the distribution of Asian Y chromosomes? And if non-random events like this can have such a profound effect on genetic diversity patterns, how could we trust molecular ‘clocks’ that depend so heavily on random mutation and random mating?

Conclusions

If the African sequences are not evolving in a clock-like manner, the Recent African Origins theory must be seriously reworked.

The studies referenced in this paper highlight the tenuous nature of the Recent African Origins theory. RAO relies deeply on the Standard Neutral Model of evolution, but every assumption behind SNM and, therefore, RAO has been openly questioned in the evolutionary literature. If the African sequences are not evolving in a clock-like manner, the Recent African Origins theory must be seriously reworked. The same would be true if selection is operating on the non-African sequences. If real-world populations violate the central assumptions of SNM, the conclusions of studies that assume SNM are not and cannot be the final word on the subject.
We can conclude that the assumptions behind SNM are not completely realistic. The real situation is much more complicated than the simplifying assumptions allow (figure 3) and several of these assumptions are either biased in favour of the conclusion or contrary to the data. Crossing over is not random. Population structure exists at all scales. Population admixture (especially if it occurred in the distant past) and gene conversion overly complicate the models. The presence of natural selection among human mitochondria removes the ‘neutral’ part of the SNM as far as RAO’s Mitochondrial Eve is concerned.
Finally, RAO and SNM are based on the belief that evolution can occur, but that it cannot affect the things that control the speed of evolution. There is no room for differences in mutation rates^30,31 among populations caused by environmental stress,^33,34 nutrition,³⁶ demographics (life-history patterns caused by cultural factors), or mutations in DNA polymerase and the DNA copying, proofreading or correcting mechanisms.^37,38
It has now been shown that the most popular evolutionary model of recent human evolution is unsatisfactory. But with what shall we replace it? The biblical model for human genetic history is still in its infancy. I hope this short article will spark creative thinking in other creation scientists, who will take up the torch by attacking evolutionary theory at its roots: but also, that they will succeed in introducing new ideas to the community at large. There is much work to be done. I have only sketched an outline and I have only hinted at several lines of thought that might be quite productive to creationist research.

Acknowledgments

The writing of this paper was heavily influenced and partially supported by J. Sanford. I would like to thank one of the reviewers in particular for an excellent critique; the manuscript was significantly improved as a result.

• The Non-Mythical Adam and Eve! Refuting errors by Francis Collins and BioLogos
• Is ‘mitochondrial Eve’ consistent with the biblical Eve?
• A shrinking date for ‘Eve’
• Mitochondrial Eve and biblical Eve are looking good: criticism of young age is premature
• The Neandertal mitochondrial genome does not support evolution
• Is there enough time in the Bible to account for all the human genetic diversity?

• Anthropology and Apemen Questions and Answers

Related Articles

• The Non-Mythical Adam and Eve!
• Is ‘mitochondrial Eve’ consistent with the biblical Eve?
• A shrinking date for ‘Eve’
• Mitochondrial Eve and biblical Eve are looking good: criticism of young age is premature
• The Neandertal mitochondrial genome does not support evolution
• Is there enough time in the Bible to account for all the human genetic diversity?

Further Reading

• Anthropology and Apemen Questions and Answers

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27. Torroni, A. et al., Harvesting the fruit of the human mtDNA tree, TRENDS in Genetics 22(6):339–345, 2006. Return to text.
28. Rozen, S. et al., Abundant gene conversion between arms of palindromes in human and ape Y chromosomes, Nature 423:873–876, 2003. Return to text.
29. Skaletsky, H. et al., The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes, Nature 423:825–838, 2003. Return to text.
30. Torroni, A. et al., Do the four clades of the mtDNA haplogroup L2 evolve at different rates? American Journal of Human Genetics 69:1348–1356, 2001. Return to text.
31. Howell, N. et al., African haplogroup L mtDNA sequences show violations of clock-like evolution, Molecular Biology and Evolution 21(10):1843–1854, 2004. Return to text.
32. Friedlaender, J. et al., Expanding Southwest Pacific mitochondrial haplogroups P and Q, Molecular Biology and Evolution 22(6):1506–1517, 2005. Return to text.
33. Mishmar, D. et al., Natural selection shaped regional mtDNA variation in humans, Proceedings of the National Academy of Sciences (USA) 100(1):171–176, 2003. Return to text.
34. Moilanen, J.S., Finnilä, S. and Majamaa, K., Lineage-specificselection in human mtDNA: lack of polymorphisms in a segment of MTND5 gene in haplogroup J, Molecular Biology and Evolution 20(12):2132–2142, 2003. Return to text.
35. Zerjal, T. et al., The genetic legacy of the Mongols, American Journal of Human Genetics 72:717–721, 2003. Return to text.
36. Ames, B., Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage, Proceedings of the National Academy of Science (USA) 103(47):17589–17594, 2006. Return to text.
37. Copeland, W.C. et al., Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders, Acta Biochemica Polonica 50(1):155–167, 2003. Return to text.
38. Lee, H.R. and Johnson, K.A., Fidelity of the Human Mitochondrial DNA Polymerase, The Journal of Biological Chemistry 281(47):36236–36240, 2006. Return to text.
39. Carter, R. Mitochondrial diversity within modern human populations, Nucleic Acids Research 35(9):3039–3045, 2007. Return to text.

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Taken from: http://creation.com/neutral-model-of-evolution-recent-african-origins

Melchizedek not a Canaanite priest

 

 

At least some of those biblical characters commonly designated by commentators as being “enlightened pagans (or Gentiles)” cannot possibly have been so, without throwing Mosaïc Law into turmoil. Some examples of this common designation would be: 1. Melchizedek (Genesis); 2. Rachab (in the genealogy of David and Jesus); 3. Ruth of Moab; 4. Achior (Book of Judith); 5. Job; and, perhaps 6. The Magi of the New Testament (and St. Stephen Protomartyr).

 

In this article, we shall be focussing very much upon 4. Achior, a supposed Ammonite, with just brief notes on the rest of 1-6.

 

Achior could not have been an Ammonite!

 

If we are to take seriously the Book of Judith, and not just relegate it (as do most commentators) to merely some ‘pious fiction’ genre, then it is impossible that Achior was an Ammonite. And the same would apply (unless there were a different law for females) to 3. Ruth, a supposed Moabite (“a prototypical Gentile who must be inspired by the teachings of our Torah”: http://www.thejewishweek.com/jewish-life/sabbath-week/conversion-ruth). For, according to Deuteronomy 23:3: “No Ammonite or Moabite may enter the LORD’s assembly; none of their descendants, even to the tenth generation, may ever enter the LORD’s assembly”. Yet of Achior it is said, upon Judith’s victory over the now headless “Holofernes”: “When Achior saw all that the God of Israel had done, he believed firmly in God. So he was circumcised, and joined the house of Israel, remaining so to this day.” – Judith 14.10 (NRSV).

Commentators struggle to deal with this apparently blatant breach of Mosaïc Law. For example (http://knightword.wordpress.com/2010/04/22/the-conversion-of-achior-judith-14-10/):

 

In … Judith 14.10, Achior becomes a proselyte within the house of Israel. It is interesting to note that at least to the author of the Book of Judith … they seemed to have no problem in letting Achior within the house of Israel. … Since it should be noted that Achior isn’t just any sort of pagan, he’s an Ammonite, a chief leaders, as evidence by Judith 5.5a “Then Achior, the leader of all the Ammonites.”

But if one remembers Deuteronomy 23.3 it reads that “No Ammonite or Moabite shall be admitted to the assembly of the Lord. Even to the tenth generation, none of their descendants shall be admitted to the assembly of the Lord,” So before even going any further, when one looks at Achior, we see in him one of the … unlikeliest men to convert to Judaism.

Despite the rule in Deuteronomy, the Book of Judith has Achior converted. There are of course a variety of different reasons given to why Achior might have been exempted from the rule. Perhaps he was a special case (as was Ruth the Moabitess), perhaps the prohibition has past, Achior being past the tenth generation, or maybe the author is even just expressing the same “universalism,” of the book of Jonah. ….

In any case, despite who Achior is racially, the author of Judith clearly wishes for him to be seen in the light of the other righteous Gentiles of the bible. … Achior is said to believe “firmly,” or “exceedingly, the greek word being σφόδρα which Crowley say “must mean ‘with all his heart,’”…. Thus Achior is indeed a genuine conversion, moreover he moves from the simple “God fearer,” sort of Gentile and now into full proselytism, and hence has “bound himself,” the laws which accompany that. …. So that in spite of all the difficulties which Achior brings, he becomes a symbolic invitation to other would be converts, to the author, Achior is not one secluded case, but instead a representative of all gentiles who would wish to come to faith in the God of Israel. …

[End of quote]

 

This interpretation, we would suggest, is not the answer. The complete story of Achior is to be found only in the Catholic Bible. Providentially, we Catholics have also for this very same historical period the Book of Tobit, whose Vulgate version likewise tells of this Achior (11:20: …. veneruntque Achior et Nabath consobrini Tobiae gaudentes …), otherwise called Ahikar.

Now, Achior (or Ahikar) was Tobit’s very nephew (Tobit 1:21-22 GNT):

 

[The Assyrian king] Esarhaddon … put Ahikar, my brother Anael’s son, in charge of all the financial affairs of the empire. This was actually the second time Ahikar was appointed to this position, for when Sennacherib was emperor of Assyria, Ahikar had been wine steward, treasurer, and accountant, and had been in charge of the official seal. Since Ahikar was my nephew, he put in a good word for me with the emperor ….

 

The Tales of Ahikar (var. Ahiqar), the inspiration for Æsop and Sinbad, are famous in literature. This Ahikar was celebrated in the ancient Near East for his outstanding wisdom. Intriguingly, some of his sayings were appropriated by ‘Mohammed’ and inserted in various Sura of the Koran (http://archive.org/stream/TheStoryOfAhikar/Ahikar_djvu.txt). But Ahikar was no more an Assyrian sage than he was an Ammonite. He was presumably, like his uncle Tobit, an Israelite from the tribe of Naphtali.

What pagan Ammonite would have been able to rattle off the history of Israel so unhesitatingly as Achior (in an historical summary reminiscent of St. Stephen’s to the Sanhedrin, Acts 7:2-47) was able to do when asked by “Holofernes”: ‘… tell me about the people who live in these mountains. Which cities do they occupy? How large is their army? What is the source of their power and strength? Who is the king who leads their army? Why have they alone, of all the people in the west, refused to come out and surrender to me?’ (Judith 5:3-4, 6-19)

This was the Achior who, though belonging to a wholly apostate tribe, except for the pious Tobit (‘But my entire tribe of Naphtali rejected the city of Jerusalem and the kings descended from David’, Tobit 1:4), had latterly come under the influence of his goodly uncle who no doubt reinforced in the mind of the young nephew all the traditions of Israel and its history. The connection of Achior with “Ammonite” in the Book of Judith is indeed problematical - though in Judith 6:5 he is differently linked, by “Holofernes”, with Ephraïm, “Achior, you and your Ephraimite soldiers”. Ephraïm (a designation for northern Israel) would indeed be more fitting for a relative of Tobit’s. In a recent article, “Ahikar Part Two: As a Convert to Yahwism” (http://www.academia.edu/7067422/Ahikar_Part_Two_As_a_Convert_to_Yahwism for Part One, see: http://www.academia.edu/7048703/Ahikar_or_Achior._Part_One), Damien Mackey rejected the possibility of Achior’s having been an Ammonite foreigner:

 

… there now arises that problem with my actual reconstruction of Achior as an Israelite in the Assyrian army, and it is this verse: “Then Achior, the leader of all the Ammonites, said to [Holofernes] ...” (5:5). Achior is said in this verse to have been an “Ammonite”; a matter we discussed in some detail … when considering why [the Book of Judith] was not accepted into the Hebrew canon. Whilst this does immediately loom as a major problem, there is one factor – apart from what has already been said about Achior – that makes his being an Ammonite highly unlikely, and this is that Achior will later, in [Judith] 14, be converted to Judaïsm and will be circumcised. The author of [Judith], who is an absolute stickler for the Mosaïc Law, and who writes in fact like a priest or Levite … would hardly have countenanced so flagrant a breach of the Law as having an Ammonite received by pious Jews into the assembly of faith, when this was clearly disallowed by Moses (Deuteronomy 23:3, 4).

Judith herself, who would so scrupulously observe all of the religious ordinances of the Law even whilst in the camp of the Assyrians [Judith] (… 12), would hardly (if she were real) have been a party to this forbidden situation.

[End of quote]

 

So, of whom was Achior actually the “leader” when he, prior to his conversion, accompanied “Holofernes” with the massive Assyrian army to Israel? Very likely, the Elamites (with whom Ammonites may have later been confused), since Tobit tells us of his blindness that (2:10): “Ahikar [Achior] … took care of me for two years, until he left for Elam”. We think that there is a verse in the Book of Judith (1:6) that echoes this, thereby binding together the eras of Tobit and Judith. We previously wrote on this (Elam and Elymaïs being synonymous):

 

There is a gloss later added to the Vulgate version of the Book of Judith which tells that "Arioch [Erioch] ruled the Elymaeans" (1:6). "Arioch" is unknown. Obviously a copyist had failed to realize that this person, given as Arioch [or Erioch], was the same as the Achior who figures so prominently throughout the main story. The copyist, it seems, should have written: "Achior ruled the Elymaeans". From there it is smooth running to make the comparison:

 

"Achior ... Elymaeans" (Judith); "Ahikar ... Elymaïs" (Tobit).

 

Typically biblical commentators, recalling that there was a foreign king, “Arioch”, way back in the Book of Genesis (14:1), whilst denying any real historical credence to the characters in the Book of Judith, ascribe mention of an Arioch in the latter to something like ‘the author’s fondness for biblical archaïsms’. In their mind, Judith, Achior, Arioch, never really existed.

For us, though, Achior was the nephew of Tobit, an Israelite from the tribe of Naphtali.

Pre-conversion, Achior also figures famously in 2 Kings, 2 Chronicles and Isaiah, as the brash Rabshakeh military officer whom we already introduced on p. 19. Thus Isaiah 36:2: “And the King of Assyria sent the Rabshakeh from Lachish to King Hezekiah at Jerusalem, with a great army”.

Not surprising that “the King of Assyria”, Sennacherib [= Book of Judith’s “Nebuchadnezzar”], might have selected this highly-talented Israelite to harangue the Jews in their own language. This was Achior as a rising prodigy in Assyrian captivity before his conversion, later, thanks to Judith’s bringing to a shuddering halt the Assyrian war machine at Bethulia (modern Mithilia).

He was not a foreigner to Israel, but apparently a “leader” (governor and captain) of foreign contingents in the mighty Assyrian army.

Notice how, in contemporary scholarship, Israel keeps getting squeezed out. ‘No one’ speaks Hebrew, instead it is Aramaïc! The same thing is happening in archaeology. Some time ago, professor Gunnar Heinsohn of the University of Bremen wrote that:

 

Mainstream scholars are in the process of deleting Ancient Israel from the history books. The entire period from Abraham the Patriarch in the -21st century (fundamentalist date) to the flowering of the Divided Kingdom in the -9th century (fundamentalist date) is found missing in the archaeological record.  

 

Even back in the days of Paul and Barnabas, the pagan Greeks were bent on appropriating these famous Jews into their own pantheon (Acts 14:12): “They decided that Barnabas was the Greek god Zeus and that Paul was Hermes, since he was the chief speaker”.

 

Anyway, getting back to the main thread of this article, there follow some brief comments on those other (apart from Achior), supposedly Gentile, biblical characters (1-6): 

 

From Melchizedek to the New Testament

 

1.MELCHIZEDEK, we suggest, was not an enlightened Canaanite priest-king at all, a pagan. The great man of faith, Abram (Abraham) was hardly going to submit to being blessed by a pagan priest (Genesis 14:19). No, Melchizedek was the great Shem, son of Noah, as according to a Jewish tradition (See our: http://amaic-abraham.blogspot.com.au/2012/09/melchizedek-was-shem-son-of-noah.html As Shem, Melchizedek was the archetypal S[h]EM-ite (Semite).

 

2.RAHAB. The Canaanite harlot, Rahab, whose “faith” both Paul (Hebrews 11:31) and James (2:25) praised, incidentally (like Jesus with the Roman centurion, Luke 7:1-10), was surely not the same woman as she who became the ancestress of David and Jesus, despite what is universally taught. To have been so would once again have meant a flouting of the Mosaïc Law, in this case Deuteronomy 7 (1-3): “When the Lord your God brings you into the land you are entering to possess, and drives out before you many nations—the Hittites, Girgashites, Amorites, Canaanites, Perizzites, Hivites and Jebusites … you must destroy them totally. … Do not intermarry with them”. R. K Phillips, in “The Truth About Rahab”, has argued for Rahab the harlot to be distinguished from the Israelite woman, Rachab (note different spelling).

http://amaic-kingdavid.blogspot.com.au/2012/09/the-genealogical-rachab-was-not.html

 

3.RUTH. She, Ruth of the Judges era, could not plausibly have been a Moabitess for those reasons already explained (Deuteronomy 23:3). The necessity for Ruth’s having been an Israelite is well argued at: http://amaic-kingdavid.blogspot.com.au/2012/09/ruth-was-israelite.html

 

4.ACHIOR. Was most certainly an Israelite, as we have already discussed at length. The mistaken notion that Achior was an Ammonite chief is perhaps the primary reason why the Jews have not accepted the Book of Judith as part of their scriptural canon.

 

5.JOB We have firmly identified Job as Tobit’s very son, Tobias, in “Job’s Life and Times”, http://www.academia.edu/3787850/Jobs_Life_and_Times Thus Job was not an enlightened Edomite (nor an Arabian sheikh), as is often thought, but a sage of Israel, a cousin of Achior.

 

6.THE MAGI. If Blessed Anne Catherine Emmerich be correct that: “The kings [Magi] were descendants of Job” (http://www.spiritdaily.net/emmerichmanger.htm), then we might conclude that the Magi’s “East” (Matthew 2:1) was the same as that of Job (1:3): “He was the greatest man among all the people of the East”. With our modern tendency to think globally, we usually pitch the Magi all the way east to Persia – for instance, enlightened Zoroastrians (those “enlightened pagans” once again). But was even Zoroaster an enlightened pagan? - for there are Syro-Arabic traditions that Zoroaster was the biblical scribe, Baruch. We think it conceivable that the Magi, as potential Transjordanian Israelites, may not have had to travel any further than the same approximate “east” wherein Job had dwelt, in the land of Uz (Transjordanian Bashan).

 

A Concluding Thought on St. Stephen Protomartyr

 

His address to the Sanhedrin reminded us a bit of Achior’s address to “Holofernes” (refer p. 24).

Could Stephen, so knowledgeable in the history of Israel, though thought to have been a Greek, actually have been an Israelite - just as Achior, so knowledgeable in the history of Israel, but thought to have been an Ammonite, was most certainly an Israelite?

Having a non-Jewish name, like “Stephen” (Greek), does not necessitate that one was not Jewish (or Israelite). Acts 18:2, for instance, introduces “a Jew named Aquila” (Latin for “eagle”). Stephen is never explicitly called a Greek, and, of the wise seven amongst whom he is listed, only “Nicolas from Antioch” is said to have been “a convert to Judaism” (6:5).

Our tentative thought is that Stephen was the Nathanael of whom Jesus had said (John 1:47): ‘Here truly is an Israelite in whom there is no deceit’. That Stephen was a true Israelite who recounted before the Sanhedrin both the history and the meaning of Israel.

Again, “Jesus said [to Nathanael], ‘You believe because I told you I saw you under the fig tree. You will see greater things than that’. He then added, ‘Very truly I tell you, you will see heaven open, and the angels of God ascending and descending on the Son of Man’.” (vv. 50-51). And so it happened (Acts 7:55-56): “But Stephen, full of the Holy Spirit, looked up to heaven and saw the glory of God, and Jesus standing at the right hand of God. ‘Look’, he said, ‘I see heaven open and the Son of Man standing at the right hand of God’.”

And did priest Caiaphas see it too? (Cf. Matthew 26:64)